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Transcriptional regulation via the action of the -ketoglutarate (KG)-dependent demethylase PHF8, which induces demethylation of histone H3 lysine 9 dimethyl (H3K9me2), has been shown to regulate CD44 expression in an iron-dependent fashion [98]

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The specific activity of GSTs towards ITCs with varying side-chain structures, including unsaturated, linear, branched and organosulfur aliphatic ITCs, as well as benzenic ITCs, was investigated with 34 cytosolic GST proteins of S